The highly popular erectile dysfunction (ED) drug Viagra was originally developed as a possible treatment for penis enlargement no surgery angina due to its ability to boost blood circulation to the heart and stimulate the release of nitric oxide (most natural male enhancement supplements contain an ingredient that helps you produce nitric oxide - more on that later). Subsequently, it turned out that Viagra was not good enough to be used as a heart medication. However, researchers noticed that it did cause frequent erections.

The rest is male enhancement history. The blue pill was approved by the Food and Drug Administration as a prescription ED medication. Millions of prescriptions have since been issued, making Viagra one of the most successful drugs of all time.