It’s important to talk with a doctor before trying this over-the-counter supplement for ED, especially if you have any underlying health conditions, or are currently taking other supplements or medications that it might interact with. Other medications used to treat ED, like Viagra and cialis use, require prescriptions and have been found to be more effective than supplements like ExtenZe. You can go in person, or opt for a telehealth service like Roman, Hims, or Lemonaid. People can experience urinary retention whether they have a penis or a vagina. Not only does the manufacturer claim that ExtenZe improves ED symptoms by increasing blood flow to the penis, but it also claims that users may experience a bigger and longer erection. See a doctor right away if you experience dizziness, gastrointestinal problems, or changes to your blood pressure or heart rate.